developed by Health Canada Intense (HCI), which consists of a 55 mL puff of 2 s duration taken every 30 s and additionally all cigarette filter tip ventilation holes blocked using a strip of Mylar adhesive tape (Health Canada, 1999). Thus, despite deficiencies in relating machine measured yields to smokers’ exposure, machine-based analysis of cigarette yields is likely to remain the prevalent method for quantifying and comparing toxicant emissions from cigarettes for some time to come (Hecht, 2012).