In natural, mangosteen is the richest known source of natural xanthones compounds, which has tremendous medical values (Radha and Mathew, 2007). Mangosteen or Garcinia mangostana is a member from the tree family of Clusiaceae or alternatively, Guttiferae and the genus- Garcinia is named after the French botanist, Laurent Garcinia (Ploetz, 2003). The pericarp of Garcinia mangostana is a source of xanthones and other bioactive substances. Hence, xanthones have been isolated from pericarp, as well as from whole fruit, heartwood, and leaves