of hypertension and diabetes. “Captopril” (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
(fig:1) is a potent, competitive, orally active Angiotension Converting Enzyme (ACE) inhibitor used for the
treatment of hypertension and some type of congestive heart failure. It works by decreasing certain chemicals that
tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently. It is also
used for preventing kidney failure due to high blood pressure and diabetes. Owing to its large prescription, it finds
adequate position in Top-Selling Drug List.