After Alexander the Great conquered the Persians, he established the city of Alexandria Eschate in 339 BCE in the Fergana Valley of Neb (modern Tajikstan). Leaving behind his wounded veterans in the city, Alexander moved on. In time, these Macedonian warriors intermarried with the indigenous populace creating the Greco-Bactrian culture which flourished under the Seleucid Empire following Alexander’s death. Under the Greco-Bactrian king Euthydemus I (260-195 BCE) the Greco-Bactrians had extended their holdings. According to the Greek historian Strabo (63-24 CE) the Greeks “extended their empire as far as the Seres” (xi.ii.i). `Seres’ was the name by which the Greeks and Romans knew China, meaning `the land where silk came from’. It is thought, then, that the first contact between China and the west came around the year 200 BCE.