3.3. In vitro bacterial mutagenicity
Strain- and S9-specific positive control substances (data not
shown) as well as TPM of the reference cigarette 2R4F produced
mutagenicity results consistent with historical data from the
laboratory.
The tester strains TA102 and TA1535, with and without S9,
were unresponsive to the treatment with TPM and are not
discussed further.