Among mycotoxins, AFs is classified as the most toxic class and mainly produced by species of Aspergillus flavus and Aspergillus parasiticus. Aflatoxin B1 (AFB1) is recognized the most acute and toxic class of AFs. The International Agency for Research on Cancer has placed AFs in group 1 carcinogen, OTA in group 2B and ZEN in group 3 carcinogens. ZEN is reported as common food contaminant especially in cereals. Mycotoxins are capable of altering immune-mediated activities in animals , or producing acute toxic, mutagenic, teratogenic, carcinogenic and estrogenic effects depending on the level of exposure.