Very few studies have investigated the effect of yeast on skin,
and no report could clearly explain the mechanism of
improvement in moisture content and elasticity. Yeast extract from
Saccharomycopsis was reported to inhibit, via gene expression of
heme-oxigenase-1, the nitric oxide from macrophages, thus
preventing the damage of epidermal cells 24). Antioxidant-enriched
yeast may promote the ability of regeneration and protect the skin
against doxorubicin toxicity 25). These results indicate that the
supplementation of yeast as an anti-oxidant may prevent the
damage of epidermal cells and enhance the ability of tissue
regeneration. It is also possible to prevent the oxidative damage of
collagen which plays a role to keep the skin elasticity. When the
regeneration of the skin is activated, it also promotes the synthesis
of collagen and ceramide which acts as a skin moisturizer. This
may be a reason that the dried brewer’s yeast improved the skin
elasticity and moisture amount in this study. In healthy adult men
who used skincare cosmetics containing hydrolyzed yeast for 2
weeks, evaluation of effects on the skin by skin imaging revealed
improvements in crows feet (wrinkles and stickiness at the corner
of the eye) 26). This result is compatible with the present findings
Very few studies have investigated the effect of yeast on skin,and no report could clearly explain the mechanism ofimprovement in moisture content and elasticity. Yeast extract fromSaccharomycopsis was reported to inhibit, via gene expression ofheme-oxigenase-1, the nitric oxide from macrophages, thuspreventing the damage of epidermal cells 24). Antioxidant-enrichedyeast may promote the ability of regeneration and protect the skinagainst doxorubicin toxicity 25). These results indicate that thesupplementation of yeast as an anti-oxidant may prevent thedamage of epidermal cells and enhance the ability of tissueregeneration. It is also possible to prevent the oxidative damage ofcollagen which plays a role to keep the skin elasticity. When theregeneration of the skin is activated, it also promotes the synthesisof collagen and ceramide which acts as a skin moisturizer. Thismay be a reason that the dried brewer’s yeast improved the skinelasticity and moisture amount in this study. In healthy adult menwho used skincare cosmetics containing hydrolyzed yeast for 2weeks, evaluation of effects on the skin by skin imaging revealedimprovements in crows feet (wrinkles and stickiness at the cornerof the eye) 26). This result is compatible with the present findings
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