Fig. 2A shows the solvent-accessible surface of arginase from L.
amazonensis, including the docked compounds in the binding pock-
et. A close up of the docking interaction with the enzyme is shown
in Fig. 2B and C. Fig. 3 shows a 2D-representation of the flavonoid-
enzyme interactions (Schomburg, Ehrlich, Stierand, & Rarey, 2010).
The intermolecular hydrogen bonds are shown as black dashed
lines in both Fig. 2B and Fig. 3. These hydrogen bonds serve as
‘‘molecular anchors’’ for binding the compounds into the enzyme
active site.