The purpose of this research is to apply the system geographic information science to study the changes of spatial amphawa. Study on land use amphawa. And to guide land use, amphawaAmphawa, Samut songkhram province area 170.164 square kilometers. The research instruments satellite photos LANDSAT 5 system TM townplanning amphawa scale. 1: 50 000, documents and information related to the Nong Han District.This research aims to study the application of Geographical Information Systems, Spatial Amphawa. Study of land use Amphawa. And to guide land use Amphawa. Research in this area, Amphoe Amphawa area of 170.164 square kilometers. Instruments used in the research base. LANDSAT 5 TM satellite system planning of Amphawa scale of 1: 50,000 and documentation related to Amphawa.