Acute hospital care for stroke patients in Germany is excellent, according to data from the ADSR for 2012. The defined target ranges are already being achieved for many of the standardized quality indicators. The wide ranges with significant differences in the degree to which individual quality indicators have been met between individual quality assurance projects show, however, that stroke care in Germany has not been fully standardized yet. No major differences exist for the quality of care between quality assurance projects with mandatory documentation compared with the overall average. The data from the ADSR‘s regional quality assurance projects are a unique data source for finding answers to further scientific questions regarding the improvement of care for stroke patients in Germany—for example, regarding the identification of institutional factors for the quality of care or the investigation of time trends in stroke care.