significant differences were not found in the rates of LOS between the 60–75 s DCC and the 30–45 s DCC groups [33].An alloimmune disorder due to maternal and fetal blood type incompatibility, is associated with fetal and neonatal complications related to red blood cell (RBC) hemolysis. A recent single-center, retrospective cohort study by Garabedian et al. highlighted that DCC may be a safe, effective, cost-free strategy to prevent the need for postnatal exchange transfusions in cases of RBC alloimmunization [62]. The authors demonstrated that DCC improved the hemoglobin level at birth and longer delay between birth and first transfusion with no severe hyperbilirubinemia. Infants with red blood cell alloimmunization benefit from DCC due to a decreased postnatal exchange and top-up transfusions needs. Thus, DCC with duration of 30 s in infants at risk for red blood cell alloimmunization neonatal anemia is recommended. It will be interesting to evaluate the long-term effects of DCC in this population.