This study determined the science inventive thinking skills of students in Brunei with regards to gender and school location. The results of the finding affirmed that students in Brunei achieved satisfactory level on four dimensions of inventive thinking skills namely adaptability and sound reasoning, risk taking, self direction and curiosity. On the other hand, the students had scored low mean on creativity and higher order thinking. Thus, the students should not confine to the traditional method of teaching and learning and inventive thinking skills should be cultivated among the students at an early age. The most important aspect of teaching pupils an inventive problem solving is to create a climate of thinking and problem solving in the class. Beyond the direct teaching of terms, thinking schemes and heuristic related to inventive thinking and problem solving, it is important to give the pupils the time and opportunity to develop their own thinking methods and explain or justify their ideas. Since an inventive thinking skill is one of the important components of 21st century skills. Students in 21st century need to apply inventive thinking skills as well as developed new skills to cope and thrive in this changing society. Therefore, 21st education should equipped students with those skills to ensure that education plays an important role in maintaining national prosperity and stimulating economic growth. The New Economy is driven by entrepreneurs, technology, and innovation. Markets in the New Economy are rewarding those who have high educational achievement and technical skill (Task Force on the Future of American Innovation, 2005). As a result, the worker of the 21st century must have science and mathematics skills, creativity, fluency in information and communication technologies, and Maria Abdullah and Kamisah Osman / Procedia Social and Behavioral Sciences 7(C) (2010) 294–301 301 the ability to solve complex problems (Business-Higher Education Forum, 2005). To accomplish this we must ensure students are equipped with those skills and engage their interest in gaining 21st century skills and knowledge.