Evidence of Benefit
Lab studies indicate that resveratrol directly inhibits the tyrosinase enzyme and also blocks it from maturing and becoming functional.257 Recently published results on a resveratrol derivative (5HNB) showed significant tyrosinase inhibition. In fact, 5HNB was far more potent than the commercially-used skin lightener kojic acid
In an animal study, dark-skinned swine treated with a topical application of 1% resveratrol showed significant skin lightening effect. Further placebo-controlled studies demonstrated that animals treated with topical resveratrol (both before and after UVB exposure) had significantly less skin-darkening than untreated animals exposed to UVB