The predicted protein lacks transit sequences
for either chloroplasts or mitochondria, suggesting it is
localized in the cytosol. Interestingly uridine has been
reported to be capable of promoting cell division in pea
roots , raising the possibility that CDA
may play a role in nodulation of legume plants .
The absence of cytosine deaminase activity
in plants has led to its development as a negative selectable
marker in several plants including Arabidopsis
.