Outside the cell
The registration peptides are cleaved and tropocollagenis formed by procollagenpeptidase.
These tropocollagenmolecules gather to form collagen fibrils, via covalent cross-linking by lysyloxidasewhich links hydroxylysineand lysine residues. Multiple collagen fibrils form into collagen fibers.
Collagen may be attached to cell membranes via several types of protein, including fibronectinand integrin.
PMT321_