Of the remaining 238 parents, 28 indicated that none of their other adult children would be involved in the future care of their sibling with schizophrenia, and thus these families were not eligible for the sibling study. For the 210 parents who indicated a sibling would be involved, we described the sibling study and asked permission to contact the most involved (or only) sibling to request his or her permission to participate in a survey distributed by mail.