In a previous work (Ruiz-Velazco et al., 2010), using data from commercial farms, we studied the impact of the white spot disease on the dynamics of intensive production of L. vannamei, establishing relationships between parameters of a stock model and management and water quality variables. This demonstrated the important role that adequate management of stocking density, pond size and, particularly, starting time of aeration (i.e. the time when it is decided to turn on aerators for the first time, regardless the dissolved oxygen level) play in generally improving cultivation conditions and mitigating negative impacts of white spot disease.