2D materials are excellent candidates for high-gain photo-detection because the charge carriers in these materials show large mobility. Thus, conductivity of this material is highly sensitive to electrostatic perturbation via photogenerated carriers adjacent to the top layer (surface). This makes 2D materials a predominantly auspicious material for extraordinary gain photo-detection by employing the photo-gating effect. Therefore, the demonstration of photodetection improvement with the 2D material would be the foundation for a plethora of applications including biomedical imaging, integrated optoelectronic devices, quantum information technology remote sensing, and optical communications. Additionally, the thickness of 2D materials gives admittance to field effects observations in the sample conductance, which is important for application in sensors and optoelectronics. In addition, the electron waves of 2D materials are accessible to complete surface characterization techniques because of one atom thick [111].