Malaria transmission occurs in all six WHO regions. Globally, an
estimated 3.3 billion people are at risk of being infected with
malaria and developing disease, and 1.2 billion are at high risk
(>1 in 1000 chance of getting malaria in a year). According to the
latest estimates, 198 million cases of malaria occurred globally
in 2013 (uncertainty range 124–283 million) and the disease
led to 584 000 deaths (uncertainty range 367 000–755 000).
The burden is heaviest in the WHO African Region, where an
estimated 90% of all malaria deaths occur, and in children aged
under 5 years, who account for 78% of all deaths.