Procalcitonin
concentration has a modestly better sensitivity than does CRP concentration but is less specific. Chiesa and colleagues have published normal values for procalcitonin concentrations in term and preterm infants.There is evidence from studies conducted in adult populations,
the majority of which focused on patients with sepsis in the ICU, that significant reductions in use of antimicrobial agents can be achieved in patients whose treatment is guided by procalcitonin concentration