The mean age-standardized IR of EOS from 1971 to 1993 was 1.80 (95% CI:
1.79, 1.82) per 100 000 person years and the mean
age-standardized IR of EOS from 1994 to 2010 was
5.15 (95% CI: 5.10, 5.20) per 100 000 person years.
Comparing the two time periods, the difference was
3.34 (95% CI: 3.29, 3.40). Age at diagnosis for each
sex is presented in Fig. 2.