HISKA® was known to be the coagulant and density enhancer for rubber latex but at the same time it was claimed to be odor reducer for rubber. This test was to ensure that the product possess antimicrobial activity against isolated microorganism. From the observation, HISKA® was found to be effective towards most of the isolated microorganism except for CUP6 as shown in Figure 4 where the zone of inhibition for Gram negative isolate was 21.5 mm as compared to E.coli (22.5 mm).