administer first dose during the first 5 days of menstrual period, or at the sixth week postpartum if breast-feeding. shake vigorously prior to administration. administer by subQ injection in the anterior thigh or abdomen; avoid boney areas and the umbilicus. administer over 5-7 seconds. donot rub the injection area. when switching from combined hormonol contraceptives (estrogen plus progestin),the firth injection should be within 7 day after the last active pill, or removal of patch or ring. lf switching from the i.m. to subQ formulation, the next dose should be given rithin the prescrinuous coverage.