Based on the illustrated tasks of a future LIS, we think this is only solvable by a new concept, laboratory data management (LDM) as duties and responsibilities cannot be solved by one huge and closed system LIS. A LDM should be a leading system which coordinates specific programs for different specialized tasks (connection of useful tools and data transfer). It has to process and provide laboratory data for specialized programs; other programs have to process and provide data for the LDM (‘give and take’/‘symbiosis’ of programs). The LDM is a modular system with an individual adaptation to the laboratory (e.g., small, high specialized laboratory or laboratory with a high throughput; for this reason some tasks are shown in Figure 2 as a single basic task or in a superior task). In addition, it is advisable for high flexibility and change of programs that the data (measurement data, medical reporting, and master data from the LIS) are saved in a form which can easily be read by another software.