the specific chemical form of the analyte (certain valenncy) is required – some ways of
sample decomposition (e.g. procedures usin HNO3 only or HNO3 + H2O2 without H2SO4)
are not suitable as oxidising agents mostly interfere with hydride generation
high concentrations of Cu, Ni, platinum group metals and other transition metals cause
serious interferences
a large excess of the hydride-forming element makes determination of traces of the other
one impossible (e.g. a lot of Se and traces of As or vice versa).