Abstract: The assesement of immunomodulatory activity of hydro-alcoholic extract of flowers of Hibiscus rosa
sinensis Linn. (75, 150 and 300 mg/kg, p.o.) and ethanolic extracts of aerial parts of Cleome gynandra Linn.
(50, 100 and 200 mg/kg, p.o.) were done by carbon clearance method for non-specific immunity,
haemagglutination antibody titre method for humoral immunity and footpad swelling method for cell mediated
immunity on wistar albino rats. Results of present studies suggest that the hydro-alcoholic extract of Hibiscus
rosa sinensis Linn. was found to possess significant immunostimulatory action on immune system but ethanolic
extract of Cleome gynandra Linn. exhibited significant immunosuppression effect in dose dependent manner
when compare with control group.
Key words: Carbon clearance method Cellular mediated immunity Haemagglutination antibody titre
Immunostimulatory action