Polyvinylpyrrolidone (PVP) is a polar molecule and is used in a wide variety of applications. For example, since it simply passes through humans, it is a binder in pharmaceutical tablets. Because PVP binds to polar molecules quite well, it is also used as a paper coating. PVP can also be found in shampoo, toothpaste, paint, and adhesives. Rapid, reliable characterization is important to better understand manufacturing performance, processing, and structure-property relationships. With the correct choice of instrument, molecular weight determination of PVP is routine.