Surgical procedures are generally considered after
the failure of two appropriate drug regimens, although
the number of unsuccessful trials with AEDs, alone or
in combination, before considering surgery remains a
matter of debate.47,49
When contemplating surgery, it
is important to assess the likelihood of seizure remis-sion using further drug regimens compared to surgi-cal resection, whilst considering the risks associated
with such procedures. Although current evidence
suggests that temporal lobe surgery is the most effec-tive treatment option after the failure of two AEDs,
the same cannot be said for other surgical procedures,
such as frontal lobe resection, whereby the overall
benefit from surgery may not be greater than trying
alternative drug regimens. In these cases, the risks
for each treatment option should be weighed up on a
case-by-case basis until more definitive data is avail-able to guide therapeutic decisions
Surgical procedures are generally considered after the failure of two appropriate drug regimens, although the number of unsuccessful trials with AEDs, alone or in combination, before considering surgery remains a matter of debate.47,49When contemplating surgery, it is important to assess the likelihood of seizure remis-sion using further drug regimens compared to surgi-cal resection, whilst considering the risks associated with such procedures. Although current evidence suggests that temporal lobe surgery is the most effec-tive treatment option after the failure of two AEDs, the same cannot be said for other surgical procedures, such as frontal lobe resection, whereby the overall benefit from surgery may not be greater than trying alternative drug regimens. In these cases, the risks for each treatment option should be weighed up on a case-by-case basis until more definitive data is avail-able to guide therapeutic decisions
การแปล กรุณารอสักครู่..
