2.6. Experimental procedures in SHR animals
After recovery, the animals were randomly assigned in three groups: 0 (control), 100, and 1000 mg of FWE digest/kg BW, respectively. Baseline (day-0) BP was recorded continuously for 24 h (10 min of every 60 min) from day 0 (baseline) to day 3 under the condition described above. FWE digest was dissolved into 50 mL of Ensure. The control group was fed with 50 mL Ensure only. At the end of the recording period, all rats were sacrificed by decapitation and wire myography was performed on isolated small mesenteric arteries.