Table 3 displays the results of methodologic qualityinvestigation. A limited number of the reviewed articles(20%) received the full score using the criteria of Jadad andcolleagues.15 The contributions of dietary intake and sunlightexposure to overall 25(OH)D concentrations were often unaccountedfor and only assessed in three articles each(20%).21,22,25,33 One article obtained the full total scorepossible of 8 points;22 however, 11 of 15 selected studies(73%) scored 4, indicative of the general poor methodologicquality of articles reporting on vitamin D supplementationand quality of life.19,20,23-25,27-31,33A summary of the effect of vitamin D supplementation onprimary outcome measures and other notable findings isshown in Figure 2. Outcomes investigated by each study werediverse and results from vitamin D supplementation oftennot significant. In all of the studies where 25(OH)D concentrationswere reported, a significant increase in serum levelsoccurred (Table 4). This is likely due to the fact that the studypopulations had suboptimal baseline 25(OH)D levels (<75nmol/L [30 ng/mL]). The effect of supplementation on 25(OH)D was medium (23% of the calculable effect sizes)24,31 orlarge (77% of the calculable effect sizes),19,21,24-26,31-33 indicatingthat vitamin D supplementation had a strong, positiveinfluence on status. Short-term (6 months’ duration),
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