It is well known that the wound healing process is a complex
physiological response to injury which is composed of several overlapping
phases containing inflammation, new tissue formation and
remodelling [1]. The main objective of using wound dressing is
to accelerate wound healing by preventing bacterial infection and
the quickening of tissue regeneration. Wound dressing materials
should possess essential properties like flexibility, durability, gas
permeability, and ability to prevent water loss.
Many collagen related products have been developed in the
past few years for the wound healing purposes; some of them are
approved by drug controlling authorities and are now commercially
available [2]. Selecting collagen as base material offers several
advantages, which has well-documented structural, physical and
chemical properties. Moreover, collagen has low antigenicity, low
inflammatory, good biocompatibility and has the ability to promote
cell attachment andproliferation.Collagenor collagenbasedmatrix
materials are the most commonly used biomaterials in the skin,
connective tissue, and nerve tissue engineering [3–5]. In addition to
its physiological properties as a natural extracellular matrix (ECM)
component, the stability and microstructure also plays a vital role