5. Conclusion
In conclusion, EF extends a remarkable antihyperglycaemic effect via
inhibition of carbohydrate hydrolysing enzymes as well as ameliorates
the diabetes induced complications by inhibiting AR and AGE related
pathways. The beneficial effects of EF in are in agreement with the positive effects of the isolated Umbelliferone and Lupeol, suggesting them
as potential antidiabetic agents. Further, our results are intricately
linked to the antioxidant activities of EF and its constituents which suggest its association with the antidiabetic properties. Also, identification
of significant amount of Umbelliferone (0.38%) and Lupeol (0.36%) in
EF provided an insight for a strong chemical basis to the alleged beneficial role of EF in antidiabetic properties. However, in vivo studies to
provide a stronger basis for these evidences are essential before it can
be established and incorporated in therapeutic procedures.