Most of studies have included heterogonous population including medical and surgical patients who developed organ failure from a wide range of causes [7]. It is now recognized that organ failure does not occur as an all-or-none phenomenon, but rather that a range of organ dys- function exists leading up to clinical failure [7]. It has been suggested that this continuous process of varying levels of organ function is designated “MODS” [8]. This change in the understanding of organ failure as a con- tinuous process has led to the development of a number of scoring systems that attempt to quantitate the degree of organ failure [9,10]. These variations in the definition of organ failure and the study of heterogeneous patient populations have made it difficult to establish the accu- rate incidence of organ failure in a given homogeneous population. Figure 2 shows the incidence of single and multiorgan failure (SOF and MOF) in various studies