The optimized direct ultrasonic probe conditions in giving thehighest extracted TMA and TPC yields with respect to ultrasonictime and amplitude were compared to an indirect ultrasonic bathsystem. Fig. 2 shows the set-up of the bath system (KC2, Kerry Ultra-sonic Bath, England) where the ultrasonic generator is powered at75 W with operating frequency of 38 kHz. The mangosteen sam-ples were pre-treated following the optimized ultrasonic exposuredurations obtained from the direct ultrasonic probe method. Thesonication times for extracting TMA using methanol and ethanolwere 15 and 5 min respectively, while for TPC extraction, the sam-ples were exposed for duration of 25 min in the ultrasonic bath forboth the extraction solvents to obtain the TMA and TPC. The con-trols are extraction process with conventional stirring process onmagnetic stirring hot plate for 1 h. All the experiments includingthe control were repeated and the measurement of TMA and TPCof each experiment run was conducted in triplicates. The resultsare expressed as mean value ± standard deviation (n = 6) and sta-tistically analyzed using Student-t’s distribution and for significantdifference if p < 0.05.