in view of these results,we propose that the short-term administration of red ginseng extract is preferable to long-term administration.many of the components including all-trans retinoic acid,egcg,alpha-ketoglutarate,litein,and zeaxanthin,have been roported to have inhibitory effect on wrinkle formation in hairless mice with UV induced photoaged skin and,in each case,long-term treatment was shown to be more effetcive than shot-term treatment