n the current scenario, both academic and industrial research mainly focuses on marine microorganisms due to its impulsive potential. These credentials initiate the present research in search of salt and alkali tolerant novel actinobacteria from unexplored A & N Islands. Our study would be the first instance in comprehensive characterization of marine actinobacteria for industrial and pharmaceutical byproducts. Enhanced salt, pH and temperature tolerance of the isolates along with their capacity to secrete commercially valuable primary and secondary metabolites emerges an attractive feature of these organisms. Further, molecular characterization approach on these biological molecules will certainly bring out a new horizon in elevated production and can avoid complex downstream process associated with conventional methods. It is concluded that very frequent and systematic screening of marine actinobacteria from different sources and locations in A & N Islands may facilitate us to isolate and characterize more novel species with admirable bioactive compounds of interest.