Jellyfish have a worldwide distribution. Their stings can cause different reactions, ranging from
cutaneous, localized, and self-limited to serious systemic or fatal ones, depending on the envenoming
species. Several first aid treatments are used to manage such stings but few have evidence behind their
use. This review of the literature describes and discusses the different related first aid and treatment
recommendations, ending with a summarized practical approach. Further randomized controlled trials
in this field are needed.