A simple and sensitive method for determination of paracetamol, based on the oxidation reaction
between paracetamol and cerium(IV) for determination of paracetamol has been described. The
fluorescencet species is an reduction product of cerium(IV) has excitation and emission wavelength at 255 and
348nm, respectively. The fluorescent intensity of the system is linear over the range of concentration 150-750 g/l
of paracetamol with detection limit and relative standard deviation(RSD) of 20 g/l, and 1.22% respectively.
The method has been applied in some real samples which gave satisfactory results.