Initially, patients identified their own donors selected
from family or friends. Subsequently, some institutions offered
the option of an anonymous donor(s). This shifts the
burden of donor identification from the patient, creates a
pool of tested healthy donors with a track record of cure,
and also avoids donors with shared genetic or environmental
susceptibilities to the recipient. Donor stool is delivered to
the institution within a few hours of passage to undergo (1)
dilution, generally with normal saline, (2) homogenization
with a blender to achieve a liquid slurry, and then (3) filtration
to remove particulate matter to facilitate administration.