it is recommended that their use should be limited to
the patients with high susceptibility for GI bleeding. A study has
reported no significant difference between using Ranitidine and
Sucralfate regarding VAP incidence, the duration of ICU admission
and mortality rate and even reported Ranitidine to be more effective
in preventing GI bleeding [21]. A review article has recommended
that the prophylactic administration of the anti-ulcer drugs should
be considered only after careful evaluation of the positive and
negative effects of the drug and the patient’s clinical condition [22].
Meanwhile, many studies recommend using different types of antiulcer
agents [21,23-25]. Our results also show a high percentage of
implementation of this preventive measure in the ICUs.