Expression changes of the genes encoding proteins associated with the structure and function of endothelial cell itself:these genes include apoptosis-related genes,adhesion molecule genes
and tight junction protein genes. Apoptosis in general is considered as a host strategy to limit the virus replication. GO function analysis revealed 317 DEGs enriched in regulation of apoptosis in HUVECs after H9N2 virus infection, and that viral particles did not significantly affect the expression of apoptosis-related genes in transcriptional activity.