Abstract Hypodontia is the congenital absence of less than six
teeth because of agenesis. The absence of teeth may be unilateral
or bilateral. There are reports showing unilateral occurrence of
permanent mandibular incisors. But agenesis of bilateral mandibular
central incisors is not well documented in the literature and
comprehensive review of literature shows paucity of data pertaining
to this anomaly. As general dentist is the first member of the health
team to diagnose and treat patients having unusual anomalies, the
knowledge of congenital absence of permanent mandibular both
central incisors is very essential to provide the most appropriate and
comprehensive dental care and treatment possible. The aim of the
present paper is to report, four cases of bilateral congenital missing
of permanent mandibular central incisors and to review the literature
regarding etiology, clinical implications and management.