Alternative DNA structures were fir

Alternative DNA structures were first identified and characterized many decades ago, using techniques such as circular dichroism (CD) to provide signature spectropolarimetry for a non-B DNA structure under specific conditions [148]; enzyme or chemical probing for many types of non-B DNA structures ([12] and references therein); structure-, rather than sequence-specific antibodies [40,149–151]; and direct visualization of some non-B DNA structures by electron microscopy, such as cruciforms, H-DNA, and (large structures containing G4 DNA on the G-rich strand and a RNA/DNA hybrid on the other.

ผลลัพธ์ (แอฟริกา) 1:

Alternatiewe DNA strukture was die eerste keer geïdentifiseer en gekenmerk baie dekades gelede, met behulp van tegnieke soos sirkulêre dichroïsme (CD) te onderteken spectropolarimetry voorsiening te maak vir 'n nie-B DNA-struktuur onder spesifieke omstandighede [148]; ensiem of chemiese indringende vir baie verskillende tipes van nie-B DNA strukture ([12] en verwysings daarin); struktuur-, eerder as ry-spesifieke teenliggame [40,149-151]; en direkte visualisering van 'n paar nie-B DNA strukture deur elektronmikroskopie, soos cruciforms, H-DNA, en (groot strukture wat G4 DNA op die G-ryk Strand en 'n RNA / DNA hibriede aan die ander kant.