The study indicated that students toward The effect of opening the ASEAN to nursing profession of students in the Faculty of Nursing at Ubon Ratchathani Rajabhat University but they were not sure that the information about ASEAN affects working hour of nurse (M=3.40) and they were sure that the information about ASEAN affects opportunity in the work of Thai nurse(M=4.43).However, the majority of the respondents agree about the effect of opening the ASEAN in many a side.