Perilla oil suppresses the production of chemical mediator in the allergy and inflammatory responses. These
essential fatty acids have been associated with benefits in a wide range of inflammatory conditions, heart diseases,
colitis/Crohn’s disease, asthma, allergies, antimicrobial, anticancer etc. Perilla is also used for nausea, sunstroke,
to induce sweating and as an antispasmodic. In vivo metabolism of polyunsaturated omega-3 fatty acids, it
mainly exists in the form of DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). These two specific omega-3 fatty acids metabolites are inserted in cell membranes throughout the body, where cellular machinery
converts them into substances which prevent abnormal clotting, reduce inflammation, and relax blood vessels and improved ventilatory parameters (Lewis 2008; Talbott and Hughes 2006; Calder 2004; James et al. 2000; Chin et al.
1992; Mattson and Grundy 1985).