Statin can be effectively used in the primary and
secondary cardiovascular prevention. Patients with
CKD have atherogenic lipid profiles and suffer from
high rates of cardiovascular morbidity and mortality
[5]. Recently, Tonelli et al. also reported that the risk
of coronary events in people with CKD was compared
with those with diabetes [6]. Although few studiesenrolled CKD only subjects to test the statin efficacy,
statins were shown to effectively lower LDL and be
safe in CKD population [8, 14]. Statins can decrease
mortality and cardiovascular events in CKD persons
without dialysis [8, 15]. Therefore, ESC guideline
suggests that LDL lowering with statin to reduce
cardiovascular disease should be considered [5].
Among our 818 CKD subjects, 581 (71.0%) patients
had lipid-lowering agent treatment and 538 (65.8%)
patients received statin treatment. Considering the
suboptimal LDL and non-HDL-C target attainment,
higher TG and lower HDL levels in the CKD
population and only equal potency statin use between
the two groups, it is mandatory to educate and
ecourage our physcians to prescribe more statins for
CKD patients.