nanoprecipitation [6] and solvent evaporation [7, 8]. It is not only protecting the core substance from the outside environment but also controlling the release of the encapsulated substance.
Recently, the biodegradable polymers have been attractive for a wide range of applications such as biomedical, pharmaceutical, food packaging and agricultural industries [9, 10]. It was used as the polymer shell for various encapsulations. It was reported the preparation of -tocopherol loaded poly -caprolactone by solvent evaporation in oil in water (O/W) system [11]. The encapsulation of
-carotene in poly(hydroxybutyrate-co-hydroxyvalerate) using the solution enhanced dispersion by supercritical fluids technique was also reported [12].
One of the most popular biodegradable polymers is poly(l-lactic acid) (PLLA) which is non-toxic and environmental friendly. It is aliphatic polyester produced from renewable resources such as corn starch or sugarcane available in Thailand. PLLA is produced from the direct polycondenzation of l-lactic acid or the ring-opening polymerization of l-lactide [13]. There are many researches reported the utilization of PLLA as polymer shell encapsulating various materials. It was reported that PLLA was used to encapsulate urea by solvent evaporation in water in oil in water system [14]. The smooth spherical capsules were formed. The influence of PLLA molecular weight on the formation of the polymer shell was also studied. Cholecystokinin composed of seven aminoacids was encapsulated in poly(lactide-co- glycolide) microspheres prepared by a multiple emulsion solvent evaporation method [15]. The study of PLLA encapsulation and release properties of encapsulated ribozymes in water-in-oil-in-water emulsion system was also carried out [16].
In this work, PLLA is used as polymer shell to encapsulate vitamin E for food application. The encapsulation of vitamin E with PLLA shell in O/W emulsion using solvent evaporation technique is studied. The influence of weight ratio of PLLA:vitamin E and molecular weight of PLLA on the encapsulation are investigated.
nanoprecipitation [6] and solvent evaporation [7, 8]. It is not only protecting the core substance from the outside environment but also controlling the release of the encapsulated substance.
Recently, the biodegradable polymers have been attractive for a wide range of applications such as biomedical, pharmaceutical, food packaging and agricultural industries [9, 10]. It was used as the polymer shell for various encapsulations. It was reported the preparation of -tocopherol loaded poly -caprolactone by solvent evaporation in oil in water (O/W) system [11]. The encapsulation of
-carotene in poly(hydroxybutyrate-co-hydroxyvalerate) using the solution enhanced dispersion by supercritical fluids technique was also reported [12].
One of the most popular biodegradable polymers is poly(l-lactic acid) (PLLA) which is non-toxic and environmental friendly. It is aliphatic polyester produced from renewable resources such as corn starch or sugarcane available in Thailand. PLLA is produced from the direct polycondenzation of l-lactic acid or the ring-opening polymerization of l-lactide [13]. There are many researches reported the utilization of PLLA as polymer shell encapsulating various materials. It was reported that PLLA was used to encapsulate urea by solvent evaporation in water in oil in water system [14]. The smooth spherical capsules were formed. The influence of PLLA molecular weight on the formation of the polymer shell was also studied. Cholecystokinin composed of seven aminoacids was encapsulated in poly(lactide-co- glycolide) microspheres prepared by a multiple emulsion solvent evaporation method [15]. The study of PLLA encapsulation and release properties of encapsulated ribozymes in water-in-oil-in-water emulsion system was also carried out [16].
In this work, PLLA is used as polymer shell to encapsulate vitamin E for food application. The encapsulation of vitamin E with PLLA shell in O/W emulsion using solvent evaporation technique is studied. The influence of weight ratio of PLLA:vitamin E and molecular weight of PLLA on the encapsulation are investigated.
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nanoprecipitation [6] and solvent evaporation [7, 8]. It is not only protecting the core substance from the outside environment but also controlling the release of the encapsulated substance.
Recently, the biodegradable polymers have been attractive for a wide range of applications such as biomedical, pharmaceutical, food packaging and agricultural industries [9, 10]. It was used as the polymer shell for various encapsulations. It was reported the preparation of -tocopherol loaded poly -caprolactone by solvent evaporation in oil in water (O/W) system [11]. The encapsulation of
-carotene in poly(hydroxybutyrate-co-hydroxyvalerate) using the solution enhanced dispersion by supercritical fluids technique was also reported [12].
One of the most popular biodegradable polymers is poly(l-lactic acid) (PLLA) which is non-toxic and environmental friendly. It is aliphatic polyester produced from renewable resources such as corn starch or sugarcane available in Thailand. PLLA is produced from the direct polycondenzation of l-lactic acid or the ring-opening polymerization of l-lactide [13]. There are many researches reported the utilization of PLLA as polymer shell encapsulating various materials. It was reported that PLLA was used to encapsulate urea by solvent evaporation in water in oil in water system [14]. The smooth spherical capsules were formed. The influence of PLLA molecular weight on the formation of the polymer shell was also studied. Cholecystokinin composed of seven aminoacids was encapsulated in poly(lactide-co- glycolide) microspheres prepared by a multiple emulsion solvent evaporation method [15]. The study of PLLA encapsulation and release properties of encapsulated ribozymes in water-in-oil-in-water emulsion system was also carried out [16].
In this work, PLLA is used as polymer shell to encapsulate vitamin E for food application. The encapsulation of vitamin E with PLLA shell in O/W emulsion using solvent evaporation technique is studied. The influence of weight ratio of PLLA:vitamin E and molecular weight of PLLA on the encapsulation are investigated.
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