n the mouse, the
binding of LCFA to lingual CD36 triggers the activation of a speci
fi
c
transduction system leading to the secretion of neurotransmitters
previously stored in TRC
[13,14]
(
Fig. 1-1
). This event produces a
speci
fi
c signal conveyed by peripheral and central nervous system
involved in the gustatory pathway
[15]
(
Fig. 1-2
). From a physio-
logical point of view, lingual CD36 was shown to contribute to the
preference for fat in mice and human
[9,10]