For example, if a person's temperature is raised to about 107 degrees Fahrenheit, the negative feedback systems stop operating. A person with a high fever has hot, dry skin if they do sweat to help cool it. Not only have the negative feedback systems shut down in such a case; the increased temperature speeds up the body chemistry, which causes the temperature to rise even more, which in turn speeds up the body chemistry even more, and so forth. This vicious cycle of positive feedback, a "runaway" process, can only end in death if not stopped.