Natural antidepressants are widely perceived to exhibit more favorable side effect profiles than conventional antidepressants and the publications examined for this review tend to support this view
However, claims that these alternative products are completely benign and devoid of side effects are not supportable.
The activity of these products is rooted in the same pharmacological principles underlying the activity of conventional antidepressants
SJW is thought to exert its mood-enhancing effects as a result of “broad spectrum” reuptake inhibition of as many as five neurotransmitters